Sequence Detail

ID/Version

P42082 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=T-lymphocyte activation antigen CD86;AltName: Full=Activation B7-2 antigen;AltName: Full=Early T-cell costimulatory molecule 1; Short=ETC-1;AltName: CD_antigen=CD86;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 309 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd86	CD86 antigen	34	100	2	14

Sequence references in MGI

J:15724 Freeman GJ, et al., Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production. J Exp Med. 1993 Dec 1;178(6):2185-92
J:18042 Chen C, et al., Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 molecule. J Immunol. 1994 May 15;152(10):4929-36
J:30027 Borriello F, et al., Differential expression of alternate mB7-2 transcripts. J Immunol. 1995 Dec 15;155(12):5490-7
J:191189 Lucas CR, et al., Prohibitins and the Cytoplasmic Domain of CD86 Cooperate To Mediate CD86 Signaling in B Lymphocytes. J Immunol. 2013 Jan 15;190(2):723-36