Sequence Detail

ID/Version

P41272 (UniProt | EBI)

Last sequence update: 1995-02-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=CD27 antigen {ECO:0000305|PubMed:8384562};AltName: Full=CD27L receptor;AltName: Full=T-cell activation antigen CD27;AltName: Full=Tumor necrosis factor receptor superfamily member 7 {ECO:0000312|MGI:MGI:88326};AltName: CD_antigen=CD27;Flags:

Provider

SWISS-PROT

Sequence

Polypeptide 250 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd27	CD27 antigen	44	98	3	16

Sequence references in MGI

J:4937 Gravestein LA, et al., Cloning and expression of murine CD27: comparison with 4-1BB, another lymphocyte-specific member of the nerve growth factor receptor family. Eur J Immunol. 1993 Apr;23(4):943-50
J:65516 Hendriks J, et al., CD27 is required for generation and long-term maintenance of T cell immunity. Nat Immunol. 2000 Nov;1(5):433-40
J:97606 Nolte MA, et al., Immune activation modulates hematopoiesis through interactions between CD27 and CD70. Nat Immunol. 2005 Apr;6(4):412-8
J:350581 Englebert K, et al., The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis. Cell Rep. 2024 Feb 20;43(3):113824