Sequence Detail

ID/Version

P39053 Q61358 Q3UNM1 Q8JZZ4 A2AN50 A2AN55 A2AN51 Q9CSY7 A2AN54 Q61360 Q9QXX1 Q5DTN7 Q61359 Q6PDM5 (UniProt | EBI)

Last sequence update: 2003-06-20
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Dynamin-1 {ECO:0000250|UniProtKB:Q05193}; EC=3.6.5.5 {ECO:0000269|PubMed:19781630};AltName: Full=Dynamin {ECO:0000303|PubMed:19781630};AltName: Full=Dynamin I {ECO:0000303|PubMed:11042120};

Provider

SWISS-PROT

Sequence

Polypeptide 867 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dnm1	dynamin 1	90	107	4	13

Sequence references in MGI

J:39830 Klocke R, et al., Dynamin genes Dnm1 and Dnm2 are located on proximal mouse chromosomes 2 and 9, respectively. Genomics. 1997 Apr 15;41(2):290-2
J:65665 Yoo J, et al., Characterization of the mouse dynamin I gene promoter and identification of sequences that direct expression in neuronal cells. Biochem J. 2000 Nov 1;351 Pt 3:661-8
J:66805 Modregger J, et al., All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis. J Cell Sci. 2000 Dec;113 Pt 24:4511-21
J:81675 Modregger J, et al., Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1. J Biol Chem. 2003 Feb 7;278(6):4160-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113994 Kim YN, et al., The endocytosis-linked protein dynamin associates with caveolin-1 and is tyrosine phosphorylated in response to the activation of a noninternalizing epidermal growth factor receptor mutant. Endocrinology. 2002 May;143(5):1726-31
J:121111 Ferguson SM, et al., A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science. 2007 Apr 27;316(5824):570-4
J:207818 Karim Z, et al., UNC119 inhibits dynamin and dynamin-dependent endocytic processes. Cell Signal. 2010 Jan;22(1):128-37
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:341398 Shi B, et al., Dynamin 1 controls vesicle size and endocytosis at hippocampal synapses. Cell Calcium. 2022 May;103:102564