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Sequence Detail
P38647 Q3UVN1 Q9CQ05 Q7TSZ0 Q3V015 Q3TW93 (UniProt | EBI) Last sequence update: 2012-10-03
Last annotation update: 2019-12-11
from provider
RecName: Full=Stress-70 protein, mitochondrial;AltName: Full=75 kDa glucose-regulated protein; Short=GRP-75;AltName: Full=Heat shock 70 kDa protein 9;AltName: Full=Mortalin;AltName: Full=Peptide-binding protein 74; Short=PBP74;AltName: Ful
Polypeptide 679 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Hspa9 heat shock protein 9 42 3 9 58
Sequence references in MGI J:4289 Wadhwa R, et al., Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype. J Biol Chem. 1993 Mar 25;268(9):6615-21
J:11836 Domanico SZ, et al., Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family. Mol Cell Biol. 1993 Jun;13(6):3598-610
J:15278 Wadhwa R, et al., Induction of cellular senescence by transfection of cytosolic mortalin cDNA in NIH 3T3 cells. J Biol Chem. 1993 Oct 25;268(30):22239-42
J:15652 Michikawa Y, et al., Antigenic protein specific for C3H strain mouse is a mitochondrial stress-70 protein. Biochem Biophys Res Commun. 1993 Oct 15;196(1):223-32
J:16068 Michikawa Y, et al., Structure and organization of the gene encoding a mouse mitochondrial stress-70 protein [published erratum appears in FEBS Lett 1994 Feb 28;340(1-2):151]. FEBS Lett. 1993 Dec 20;336(1):27-33
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:233573 Chen TH, et al., Knockdown of Hspa9, a del(5q31.2) gene, results in a decrease in hematopoietic progenitors in mice. Blood. 2011 Feb 3;117(5):1530-9
J:248459 Shan Y, et al., Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly. Mitochondrion. 2016 Jan;26:94-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory