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Sequence Detail
P37238 (UniProt | EBI) Last sequence update: 2001-04-27
Last annotation update: 2018-04-25
from provider
RecName: Full=Peroxisome proliferator-activated receptor gamma; Short=PPAR-gamma;AltName: Full=Nuclear receptor subfamily 1 group C member 3;
Polypeptide 505 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Pparg peroxisome proliferator activated receptor gamma 154 26 8 39
Sequence references in MGI J:15412 Chen F, et al., Identification of two mPPAR related receptors and evidence for the existence of five subfamily members. Biochem Biophys Res Commun. 1993 Oct 29;196(2):671-7
J:16085 Zhu Y, et al., Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. J Biol Chem. 1993 Dec 25;268(36):26817-20
J:18815 Tontonoz P, et al., mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev. 1994 May 15;8(10):1224-34
J:19422 Kliewer SA, et al., Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7355-9
J:22537 Tontonoz P, et al., Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha. Nucleic Acids Res. 1994 Dec 25;22(25):5628-34
J:33358 Vidal-Puig A, et al., Regulation of PPAR gamma gene expression by nutrition and obesity in rodents. J Clin Invest. 1996 Jun 1;97(11):2553-61
J:43438 Zhu Y, et al., Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor. J Biol Chem. 1997 Oct 10;272(41):25500-6
J:62059 Zhu Y, et al., Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR. J Biol Chem. 2000 May 5;275(18):13510-6
J:95883 Drori S, et al., Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev. 2005 Feb 1;19(3):362-75
J:125396 Li D, et al., Constitutive Coactivator of Peroxisome Proliferator-Activated Receptor (PPAR{gamma}), a Novel Coactivator of PPAR{gamma} that Promotes Adipogenesis. Mol Endocrinol. 2007 Oct;21(10):2320-33
J:138823 Seale P, et al., PRDM16 controls a brown fat/skeletal muscle switch. Nature. 2008 Aug 21;454(7207):961-7
J:144377 Wang N, et al., Vascular PPARgamma controls circadian variation in blood pressure and heart rate through Bmal1. Cell Metab. 2008 Dec;8(6):482-91
J:161288 Kawai M, et al., A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-gamma nuclear translocation. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10508-13
J:167907 Grimaldi B, et al., PER2 controls lipid metabolism by direct regulation of PPARgamma. Cell Metab. 2010 Nov 3;12(5):509-20
J:178732 Hinds TD Jr, et al., Protein Phosphatase 5 Mediates Lipid Metabolism through Reciprocal Control of Glucocorticoid Receptor and Peroxisome Proliferator-activated Receptor-gamma (PPARgamma). J Biol Chem. 2011 Dec 16;286(50):42911-22
J:181224 Ji S, et al., O-GlcNAc modification of PPARgamma reduces its transcriptional activity. Biochem Biophys Res Commun. 2012 Jan 27;417(4):1158-63
J:209483 Wang F, et al., SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma. Mol Biol Cell. 2009 Feb;20(3):801-8
J:219351 Guo C, et al., The optimal corepressor function of nuclear receptor corepressor (NCoR) for peroxisome proliferator-activated receptor gamma requires G protein pathway suppressor 2. J Biol Chem. 2015 Feb 6;290(6):3666-79

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last database update
MGI 6.12
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