Sequence Detail

ID/Version

P35550 Q99L58 (UniProt | EBI)

Last sequence update: 2005-08-30
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=rRNA 2'-O-methyltransferase fibrillarin; EC=2.1.1.- {ECO:0000305|PubMed:32017896};AltName: Full=Histone-glutamine methyltransferase;AltName: Full=Nucleolar protein 1;AltName: Full=U6 snRNA 2'-O-methyltransferase fibrillarin {ECO:0000

Provider

SWISS-PROT

Sequence

Polypeptide 327 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fbl	fibrillarin	62	110	3	17

Sequence references in MGI

J:15452 Turley SJ, et al., Molecular cloning and sequence analysis of U3 snoRNA-associated mouse fibrillarin. Biochim Biophys Acta. 1993 Oct 19;1216(1):119-22
J:286260 Wang X, et al., LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice. Mol Cell. 2020 Mar 5;77(5):999-1013.e6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:302700 Zhang J, et al., Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing. Cell Death Differ. 2019 Jul;26(7):1251-1266