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Sequence Detail
ID/Version
P35546 Q8BQ34 Q9QXH9 (UniProt | EBI) Last sequence update: 2004-08-16
Last annotation update: 2014-07-09
Sequence
description
from provider
RecName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret; EC=2.7.10.1;AltName: Full=Proto-oncogene c-Ret;Contains: RecName: Full=Soluble RET kinase fragment;Contains: RecName: Full=Extracellular cell-membrane anchored RET cadherin 120 k
Provider SWISS-PROT
Sequence
Polypeptide 1115 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ret ret proto-oncogene 60 52 5 45
Sequence references in MGI J:41301 Iwamoto T, et al., cDNA cloning of mouse ret proto-oncogene and its sequence similarity to the cadherin superfamily. Oncogene. 1993 Apr;8(4):1087-91
J:70544 Grimm J, et al., Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation. J Cell Biol. 2001 Jul 23;154(2):345-54
J:87966 Shi N, et al., Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain. J Biol Chem. 2004 Feb 6;279(6):4962-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:120816 Veiga-Fernandes H, et al., Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis. Nature. 2007 Mar 29;446(7135):547-51
J:138788 Tsui CC, et al., CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction. J Neurosci. 2008 Aug 27;28(35):8789-800
J:159107 Golden JP, et al., RET signaling is required for survival and normal function of nonpeptidergic nociceptors. J Neurosci. 2010 Mar 17;30(11):3983-94

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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory