Sequence Detail

ID/Version

P35438 A2AI15 A2AI18 Q8CFS4 (UniProt | EBI)

Last sequence update: 1994-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Glutamate receptor ionotropic, NMDA 1 {ECO:0000305}; Short=GluN1;AltName: Full=Glutamate [NMDA] receptor subunit zeta-1;AltName: Full=N-methyl-D-aspartate receptor subunit NR1; Short=NMD-R1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 938 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	243	128	4	39

Sequence references in MGI

J:2285 Yamazaki M, et al., Cloning, expression and modulation of a mouse NMDA receptor subunit. FEBS Lett. 1992 Mar 23;300(1):39-45
J:66345 Forrest D, et al., Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron. 1994 Aug;13(2):325-38
J:114130 Matsuda K, et al., Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptors. J Neurosci. 2003 Nov 5;23(31):10064-73
J:169206 Labrie V, et al., Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice. Genes Brain Behav. 2010 Feb;9(1):11-25
J:198375 Wang X, et al., Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. Nat Med. 2013 Apr;19(4):473-80
J:222234 Ferreira JS, et al., GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome. J Neurosci. 2015 Jun 3;35(22):8462-79
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:354155 Matsuda K, et al., Cloning and characterization of a novel NMDA receptor subunit NR3B: a dominant subunit that reduces calcium permeability. Brain Res Mol Brain Res. 2002 Apr 30;100(1-2):43-52
J:360498 Matsui T, et al., Functional comparison of D-serine and glycine in rodents: the effect on cloned NMDA receptors and the extracellular concentration. J Neurochem. 1995 Jul;65(1):454-8