Sequence Detail

ID/Version

P35413 Q3USD4 (UniProt | EBI)

Last sequence update: 1994-06-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=G-protein coupled receptor 3;AltName: Full=GPCR21;

Provider

SWISS-PROT

Sequence

Polypeptide 330 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gpr3	G-protein coupled receptor 3	10	98	3	9

Sequence references in MGI

J:16169 Saeki Y, et al., Molecular cloning of a novel putative G protein-coupled receptor (GPCR21) which is expressed predominantly in mouse central nervous system. FEBS Lett. 1993 Dec 27;336(2):317-22
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:105182 Ledent C, et al., Premature ovarian aging in mice deficient for Gpr3. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8922-6
J:147381 Valverde O, et al., GPR3 receptor, a novel actor in the emotional-like responses. PLoS One. 2009;4(3):e4704
J:244370 Godlewski G, et al., Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue. Sci Rep. 2015 Oct 12;5:14953
J:316009 Sveidahl Johansen O, et al., Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis. Cell. 2021 Jun 24;184(13):3502-3518.e33
J:319794 Tanaka S, et al., GPR3 accelerates neurite outgrowth and neuronal polarity formation via PI3 kinase-mediating signaling pathway in cultured primary neurons. Mol Cell Neurosci. 2022 Jan;118:103691