Sequence Detail

ID/Version

P35377 Q9QUT5 Q9Z2M8 Q60645 Q9Z2N0 Q8VI74 Q9Z2M9 (UniProt | EBI)

Last sequence update: 1994-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Nociceptin receptor;AltName: Full=K3 opiate receptor;AltName: Full=Kappa-type 3 opioid receptor; Short=KOR-3;AltName: Full=ORGC;AltName: Full=Orphanin FQ receptor;

Provider

SWISS-PROT

Sequence

Polypeptide 367 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Oprl1	opioid receptor-like 1	50	104	3	11

Sequence references in MGI

J:22019 Nishi M, et al., Structure and chromosomal mapping of genes for the mouse kappa-opioid receptor and an opioid receptor homologue (MOR-C). Biochem Biophys Res Commun. 1994 Dec 15;205(2):1353-7
J:28344 Pan YX, et al., Cloning and functional characterization through antisense mapping of a kappa 3-related opioid receptor. Mol Pharmacol. 1995 Jun;47(6):1180-8
J:28352 Halford WP, et al., Functional role and sequence analysis of a lymphocyte orphan opioid receptor. J Neuroimmunol. 1995 Jun;59(1-2):91-101
J:39955 Nishi M, et al., Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor. EMBO J. 1997 Apr 15;16(8):1858-64
J:40707 Matthes H, et al., Functional selectivity of orphanin FQ for its receptor coexpressed with potassium channel subunits in Xenopus laevis oocytes. Mol Pharmacol. 1996 Sep;50(3):447-50
J:50054 Pan YX, et al., Identification and differential regional expression of KOR-3/ORL-1 gene splice variants in mouse brain. FEBS Lett. 1998 Sep 11;435(1):65-8
J:89677 Depner UB, et al., Normal sensitivity to acute pain, but increased inflammatory hyperalgesia in mice lacking the nociceptin precursor polypeptide or the nociceptin receptor. Eur J Neurosci. 2003 Jun;17(11):2381-7
J:102658 Bertorelli R, et al., Lack of the nociceptin receptor does not affect acute or chronic nociception in mice. Peptides. 2002 Sep;23(9):1589-96