Sequence Detail

ID/Version

P34884 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Macrophage migration inhibitory factor; Short=MIF; EC=5.3.2.1 {ECO:0000269|PubMed:10933783, ECO:0000269|PubMed:16780921, ECO:0000269|PubMed:19188446};AltName: Full=Delayed early response protein 6; Short=DER6;AltName:

Provider

SWISS-PROT

Sequence

Polypeptide 115 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mif	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	111	107	6	20

Sequence references in MGI

J:4010 Wistow GJ, et al., A macrophage migration inhibitory factor is expressed in the differentiating cells of the eye lens. Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1272-5
J:15428 Mikayama T, et al., Molecular cloning and functional expression of a cDNA encoding glycosylation-inhibiting factor. Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10056-60
J:24240 Mitchell R, et al., Cloning and characterization of the gene for mouse macrophage migration inhibitory factor (MIF). J Immunol. 1995 Apr 15;154(8):3863-70
J:25567 Kozak CA, et al., Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes. Genomics. 1995 Jun 10;27(3):405-11
J:27222 Bernhagen J, et al., MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia. Nature. 1993 Oct 21;365(6448):756-9
J:27223 Lanahan A, et al., Growth factor-induced delayed early response genes. Mol Cell Biol. 1992 Sep;12(9):3919-29
J:27402 Bozza M, et al., Structural characterization and chromosomal location of the mouse macrophage migration inhibitory factor gene and pseudogenes. Genomics. 1995 Jun 10;27(3):412-9
J:147772 Fingerle-Rowson G, et al., A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation. Mol Cell Biol. 2009 Apr;29(7):1922-32
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89