Sequence Detail

ID/Version

P33896 Q80UJ3 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Interferon alpha/beta receptor 1; Short=IFN-R-1; Short=IFN-alpha/beta receptor 1;AltName: Full=Type I interferon receptor 1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 590 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ifnar1	interferon (alpha and beta) receptor 1	41	106	2	37

Sequence references in MGI

J:1063 Uze G, et al., Behavior of a cloned murine interferon alpha/beta receptor expressed in homospecific or heterospecific background. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4774-8
J:21216 Lutfalla G, et al., Structure of the murine interferon alpha/beta receptor-encoding gene: high-frequency rearrangements in the interferon-resistant L1210 cell line. Gene. 1994 Oct 21;148(2):343-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:145466 Stetson DB, et al., Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell. 2008 Aug 22;134(4):587-98
J:203788 Zheng H, et al., A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses. Cell Rep. 2013 Oct 17;5(1):180-93
J:208239 de Weerd NA, et al., Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1. Nat Immunol. 2013 Sep;14(9):901-7
J:228118 Kumar KG, et al., SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor. EMBO J. 2003 Oct 15;22(20):5480-90