Sequence Detail

ID/Version

P32442 Q543E8 (UniProt | EBI)

Last sequence update: 1993-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Homeobox protein MOX-1;AltName: Full=Mesenchyme homeobox 1;

Provider

SWISS-PROT

Sequence

Polypeptide 253 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Meox1	mesenchyme homeobox 1	32	167	3	19

Sequence references in MGI

J:3682 Candia AF, et al., Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development. 1992 Dec;116(4):1123-36
J:84754 Mankoo BS, et al., The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. Development. 2003 Oct;130(19):4655-64
J:89068 Rodrigo I, et al., Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter. Mol Cell Biol. 2004 Apr;24(7):2757-66
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134681 Wasteson P, et al., Developmental origin of smooth muscle cells in the descending aorta in mice. Development. 2008 May;135(10):1823-32
J:152861 Skuntz S, et al., Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton. Dev Biol. 2009 Aug 15;332(2):383-95
J:213897 Douville JM, et al., Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells. PLoS One. 2011;6(12):e29099