Sequence Detail

ID/Version

P31996 Q5F2A8 Q9DD15 Q3S4A9 O54688 O70321 (UniProt | EBI)

Last sequence update: 1993-07-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Macrosialin;AltName: CD_antigen=CD68;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 326 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd68	CD68 antigen	23	110	3	23

Sequence references in MGI

J:4745 Holness CL, et al., Macrosialin, a mouse macrophage-restricted glycoprotein, is a member of the lamp/lgp family. J Biol Chem. 1993 May 5;268(13):9661-6
J:46248 Li AC, et al., The macrosialin promoter directs high levels of transcriptional activity in macrophages dependent on combinatorial interactions between PU.1 and c-Jun. J Biol Chem. 1998 Feb 27;273(9):5389-99
J:48338 Jiang Z, et al., Structure, organization, and chromosomal mapping of the gene encoding macrosialin, a macrophage-restricted protein. Genomics. 1998 Jun 1;50(2):199-205
J:51105 Greaves DR, et al., Functional comparison of the murine macrosialin and human CD68 promoters in macrophage and nonmacrophage cell lines. Genomics. 1998 Nov 15;54(1):165-8
J:57450 Miyashita A, et al., Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11. Gene. 1999 Sep 3;237(1):53-60
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89