Sequence Detail

ID/Version

P31695 Q9R1W9 O88314 Q62389 O35442 Q62390 A2CG28 O88316 Q9R1X0 (UniProt | EBI)

Last sequence update: 2019-04-10
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Neurogenic locus notch homolog protein 4 {ECO:0000250|UniProtKB:Q99466}; Short=Notch 4;Contains: RecName: Full=Transforming protein Int-3;Contains: RecName: Full=Notch 4 extracellular truncation;Contains: RecName: Full=Notch 4 int

Provider

SWISS-PROT

Sequence

Polypeptide 1964 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Notch4	notch 4	37	130	2	23

Sequence references in MGI

J:1812 Robbins J, et al., Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells. J Virol. 1992 Apr;66(4):2594-9
J:34181 Uyttendaele H, et al., Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development. 1996 Jul;122(7):2251-9
J:40039 Gallahan D, et al., The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4). Oncogene. 1997 Apr 24;14(16):1883-90
J:54948 Lee JS, et al., Intracisternal type A particle-mediated activation of the Notch4/int3 gene in a mouse mammary tumor: generation of truncated Notch4/int3 mRNAs by retroviral splicing events. J Virol. 1999 Jun;73(6):5166-71
J:69406 Uyttendaele H, et al., Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5643-8
J:86796 Xie T, et al., Analysis of the gene-dense Major Histocompatibility Complex class III region and its comparison to mouse. Genome Res. 2003 Dec;13(12):2621-36
J:88983 Wu L, et al., Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene. Gene. 2004 Mar 17;328:153-65
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89