Sequence Detail

ID/Version

P31482 Q60871 (UniProt | EBI)

Last sequence update: 2003-06-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Phospholipase A2, membrane associated; EC=3.1.1.4 {ECO:0000269|PubMed:8425615};AltName: Full=Enhancing factor; Short=EF;AltName: Full=GIIC sPLA2;AltName: Full=Group IIA phospholipase A2;AltName: Full=Phosphatidylcholine 2-acy

Provider

SWISS-PROT

Sequence

Polypeptide 146 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Pseudogene	Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	61	101	2	10

Sequence references in MGI

J:14670 Mulherkar R, et al., Enhancing factor, a Paneth cell specific protein from mouse small intestines: predicted amino acid sequence from RT-PCR amplified cDNA and its expression [published erratum appears in Biochem Biophys Res Commun 1993 Nov 30;197(1):351]. Biochem Biophys Res Commun. 1993 Sep 30;195(3):1254-63
J:26137 MacPhee M, et al., The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia. Cell. 1995 Jun 16;81(6):957-66
J:28799 Kennedy BP, et al., A natural disruption of the secretory group II phospholipase A2 gene in inbred mouse strains. J Biol Chem. 1995 Sep 22;270(38):22378-85
J:38328 Mulherkar R, et al., Enhancing factor protein from mouse small intestines belongs to the phospholipase A2 family. FEBS Lett. 1993 Feb 15;317(3):263-6
J:74678 Koduri RS, et al., Bactericidal properties of human and murine groups I, II, V, X, and XII secreted phospholipases A(2). J Biol Chem. 2002 Feb 22;277(8):5849-57
J:238240 Schewe M, et al., Secreted Phospholipases A2 Are Intestinal Stem Cell Niche Factors with Distinct Roles in Homeostasis, Inflammation, and Cancer. Cell Stem Cell. 2016 Jul 07;19(1):38-51
J:335553 Laine VJ, et al., Protection by group II phospholipase A2 against Staphylococcus aureus. J Immunol. 1999 Jun 15;162(12):7402-8