Sequence Detail

ID/Version

P31360 A2AJY1 (UniProt | EBI)

Last sequence update: 1993-07-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=POU domain, class 3, transcription factor 2;AltName: Full=Brain-specific homeobox/POU domain protein 2; Short=Brain-2; Short=Brn-2;AltName: Full=Nervous system-specific octamer-binding transcription factor N-Oct-3;AltName: Fu

Provider

SWISS-PROT

Sequence

Polypeptide 445 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pou3f2	POU domain, class 3, transcription factor 2	59	144	4	8

Sequence references in MGI

J:487 Hara Y, et al., Structure and evolution of four POU domain genes expressed in mouse brain. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3280-4
J:137911 Hoser M, et al., Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors. Mol Cell Biol. 2008 Aug;28(15):4675-87
J:173070 Dy P, et al., The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Nucleic Acids Res. 2008 May;36(9):3101-17
J:239195 Li R, et al., Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells. PLoS One. 2014;9(3):e92105
J:241054 Wapinski OL, et al., Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell. 2013 Oct 24;155(3):621-35