Sequence Detail

ID/Version

P31240 Q6P3C4 (UniProt | EBI)

Last sequence update: 1993-07-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Platelet-derived growth factor subunit B; Short=PDGF subunit B;AltName: Full=PDGF-2;AltName: Full=Platelet-derived growth factor B chain;AltName: Full=Platelet-derived growth factor beta polypeptide;AltName: Full=Proto-oncogene c-Sis

Provider

SWISS-PROT

Sequence

Polypeptide 241 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pdgfb	platelet derived growth factor, B polypeptide	176	124	4	16

Sequence references in MGI

J:11239 Bonthron DT, et al., Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding the B chain of platelet-derived growth factor. Genomics. 1991 May;10(1):287-92
J:20017 Leveen P, et al., Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities. Genes Dev. 1994 Aug 15;8(16):1875-87
J:41523 Lindahl P, et al., Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 1997 Jul 11;277(5323):242-5
J:68422 Kaminski WE, et al., Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF beta-receptor null mice. Blood. 2001 Apr 1;97(7):1990-8