Sequence Detail

ID/Version

P29812 Q6NXI2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=L-dopachrome tautomerase {ECO:0000305}; Short=DCT; Short=DT; EC=5.3.3.12 {ECO:0000269|PubMed:1537333};AltName: Full=DOPAchrome conversion factor {ECO:0000303|PubMed:1537333};AltName: Full=DOPAchrome isomerase {ECO:000

Provider

SWISS-PROT

Sequence

Polypeptide 517 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dct	dopachrome tautomerase	38	144	2	19

Sequence references in MGI

J:1961 Jackson IJ, et al., A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus. EMBO J. 1992 Feb;11(2):527-35
J:1962 Tsukamoto K, et al., A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase. EMBO J. 1992 Feb;11(2):519-26
J:28826 Budd PS, et al., Structure of the mouse tyrosinase-related protein-2/dopachrome tautomerase (Tyrp2/Dct) gene and sequence of two novel slaty alleles. Genomics. 1995 Sep 1;29(1):35-43
J:230050 Marubashi S, et al., RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes. J Biol Chem. 2016 Jan 15;291(3):1427-40
J:314755 Pennamen P, et al., Dopachrome tautomerase variants in patients with oculocutaneous albinism. Genet Med. 2021 Mar;23(3):479-487