Sequence Detail

ID/Version

P28867 Q91V85 Q9Z333 (UniProt | EBI)

Last sequence update: 2002-03-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Protein kinase C delta type {ECO:0000305}; EC=2.7.11.13 {ECO:0000269|PubMed:22265677};AltName: Full=Tyrosine-protein kinase PRKCD; EC=2.7.10.2;AltName: Full=nPKC-delta;Contains: RecName: Full=Protein kinase C delta type regu

Provider

SWISS-PROT

Sequence

Polypeptide 674 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prkcd	protein kinase C, delta	151	121	4	27

Sequence references in MGI

J:2328 Mizuno K, et al., Structure and properties of a ubiquitously expressed protein kinase C, nPKC delta. Eur J Biochem. 1991 Dec 18;202(3):931-40
J:11370 Mischak H, et al., Mouse protein kinase C-delta, the major isoform expressed in mouse hemopoietic cells: sequence of the cDNA, expression patterns, and characterization of the protein. Biochemistry. 1991 Aug 13;30(32):7925-31
J:76134 Mecklenbrauker I, et al., Protein kinase Cdelta controls self-antigen-induced B-cell tolerance. Nature. 2002 Apr 25;416(6883):860-5
J:76135 Miyamoto A, et al., Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta. Nature. 2002 Apr 25;416(6883):865-9
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:155211 Cheng N, et al., A critical role of protein kinase C delta activation loop phosphorylation in formyl-methionyl-leucyl-phenylalanine-induced phosphorylation of p47(phox) and rapid activation of nicotinamide adenine dinucleotide phosphate oxidase. J Immunol. 2007 Dec 1;179(11):7720-8
J:181290 Strasser D, et al., Syk kinase-coupled C-type lectin receptors engage protein kinase C-sigma to elicit Card9 adaptor-mediated innate immunity. Immunity. 2012 Jan 27;36(1):32-42
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89