Sequence Detail

ID/Version

P28825 B0V2P9 Q91WH9 (UniProt | EBI)

Last sequence update: 2010-07-13
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Meprin A subunit alpha; EC=3.4.24.18;AltName: Full=Endopeptidase-2;AltName: Full=MEP-1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 747 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mep1a	meprin 1 alpha	25	104	4	7

Sequence references in MGI

J:824 Jiang W, et al., The alpha subunit of meprin A. Molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the alpha and beta subunits [published erratum appears in J Biol Chem 1992 Jul 5;267(19):13779]. J Biol Chem. 1992 May 5;267(13):9185-93
J:17708 Gorbea CM, et al., Homo- and heterotetrameric forms of the membrane-bound metalloendopeptidases meprin A and B. Arch Biochem Biophys. 1991 Nov 1;290(2):549-53
J:32790 Beynon RJ, et al., Characterization of the soluble, secreted form of urinary meprin. Biochem J. 1996 Apr 15;315(Pt 2):461-5
J:40070 Jiang W, et al., Correlation of the exon/intron organization to the secondary structures of the protease domain of mouse meprin alpha subunit. Gene. 1997 Apr 11;189(1):65-71
J:117606 Ishmael SS, et al., Protease domain glycans affect oligomerization, disulfide bond formation, and stability of the meprin A metalloprotease homo-oligomer. J Biol Chem. 2006 Dec 8;281(49):37404-15
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89