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Sequence Detail
ID/Version
P28474 Q3TW83 Q8C662 (UniProt | EBI) Last sequence update: 2007-01-23
Last annotation update: 2025-06-18
Sequence
description
from provider
RecName: Full=Alcohol dehydrogenase class-3 {ECO:0000305}; EC=1.1.1.1 {ECO:0000250|UniProtKB:P11766};AltName: Full=Alcohol dehydrogenase 2;AltName: Full=Alcohol dehydrogenase 5;AltName: Full=Alcohol dehydrogenase B2; Short=ADH-B2;AltName:
Provider SWISS-PROT
Sequence
Polypeptide 374 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide 47 106 3 33
Sequence references in MGI J:25079 Zgombic-Knight M, et al., Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family. J Biol Chem. 1995 May 5;270(18):10868-77
J:32800 Foglio MH, et al., Characterization of the functional gene encoding mouse class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase) and an unexpressed processed pseudogene with an intact open reading frame. Eur J Biochem. 1996 Apr 15;237(2):496-504
J:33621 Hur MW, et al., Molecular cloning of mouse alcohol dehydrogenase-B2 cDNA: nucleotide sequences of the class III ADH genes evolve slowly even for silent substitutions. DNA Seq. 1992;3(3):167-75
J:88337 Liu L, et al., Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell. 2004 Feb 20;116(4):617-28
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory