Sequence Detail

ID/Version

P28301 (UniProt | EBI)

Last sequence update: 1992-12-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Protein-lysine 6-oxidase; EC=1.4.3.13 {ECO:0000269|PubMed:27432961};AltName: Full=Lysyl oxidase;AltName: Full=Ras excision protein;Contains: RecName: Full=Protein-lysine 6-oxidase, long form {ECO:0000250|UniProtKB:P28300};Contains:

Provider

SWISS-PROT

Sequence

Polypeptide 411 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lox	lysyl oxidase	91	112	3	12

Sequence references in MGI

J:4957 Contente S, et al., Structure of the mouse lysyl oxidase gene. Genomics. 1993 May;16(2):395-400
J:105910 Thomassin L, et al., The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers. J Biol Chem. 2005 Dec 30;280(52):42848-55
J:161705 Maruhashi T, et al., Interaction between periostin and BMP-1 promotes proteolytic activation of lysyl oxidase. J Biol Chem. 2010 Apr 23;285(17):13294-303
J:237691 Lee VS, et al., Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans. Proc Natl Acad Sci U S A. 2016 Aug 02;113(31):8759-64