Sequence Detail

ID/Version

P27870 Q8BTV7 (UniProt | EBI)

Last sequence update: 1992-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Proto-oncogene vav;AltName: Full=p95vav;

Provider

SWISS-PROT

Sequence

Polypeptide 845 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Vav1	vav 1 oncogene	53	102	2	23

Sequence references in MGI

J:36579 Coppola J, et al., Mechanism of activation of the vav protooncogene. Cell Growth Differ. 1991 Feb;2(2):95-105
J:43401 Katzav S, et al., Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential. Mol Cell Biol. 1991 Apr;11(4):1912-20
J:76896 Bachmaier K, et al., Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature. 2000 Jan 13;403(6766):211-6
J:76897 Chiang YJ, et al., Cbl-b regulates the CD28 dependence of T-cell activation. Nature. 2000 Jan 13;403(6766):216-20
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:118143 Kostenko EV, et al., Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs. Mol Cell Biol. 2006 Dec;26(23):8964-75
J:148303 Samuels AL, et al., Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation. Blood. 2009 Apr 16;113(16):3845-56
J:209882 Roncagalli R, et al., Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub. Nat Immunol. 2014 Apr;15(4):384-392
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89