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Sequence Detail
ID/Version
P27612 A4QPD6 Q8C6C4 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Phospholipase A-2-activating protein; Short=PLA2P; Short=PLAP;
Provider SWISS-PROT
Sequence
Polypeptide 794 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Plaa phospholipase A2, activating protein 44 96 3 29
Sequence references in MGI J:28370 Wang H, et al., Cloning of a rat cDNA encoding a protein with high homology to mouse phospholipase A2-activating protein. Gene. 1995 Aug 19;161(2):237-41
J:28587 Clark MA, et al., Cloning of a phospholipase A2-activating protein. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5418-22
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:240526 Hall EA, et al., PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins. Am J Hum Genet. 2017 May 4;100(5):706-724
J:250427 Falik Zaccai TC, et al., Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy. Brain. 2017 Feb;140(2):370-386
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory