Sequence Detail

ID/Version

P27467 (UniProt | EBI)

Last sequence update: 1992-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Protein Wnt-3a;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 352 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wnt3a	wingless-type MMTV integration site family, member 3A	191	206	3	20

Sequence references in MGI

J:11028 Roelink H, et al., Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube. Genes Dev. 1991 Mar;5(3):381-8
J:16716 Takada S, et al., Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev. 1994 Jan;8(2):174-89
J:63226 Tanaka K, et al., The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem. 2000 Jul;267(13):4300-11
J:187646 Zhang X, et al., Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation. Cell. 2012 Jun 22;149(7):1565-77
J:216033 Rios-Esteves J, et al., Identification of key residues and regions important for porcupine-mediated Wnt acylation. J Biol Chem. 2014 Jun 13;289(24):17009-19
J:219624 Takada R, et al., Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. Dev Cell. 2006 Dec;11(6):791-801
J:221496 Zhang X, et al., Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation. Dev Cell. 2015 Mar 23;32(6):719-30
J:255336 Mihara E, et al., Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/alpha-albumin. Elife. 2016 Feb 23;5:e11621