Sequence Detail

ID/Version

P27090 Q91VP5 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transforming growth factor beta-2 proprotein;Contains: RecName: Full=Latency-associated peptide; Short=LAP;Contains: RecName: Full=Transforming growth factor beta-2; Short=TGF-beta-2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 414 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tgfb2	transforming growth factor, beta 2	275	201	3	10

Sequence references in MGI

J:24256 Miller DA, et al., Murine transforming growth factor-beta 2 cDNA sequence and expression in adult tissues and embryos. Mol Endocrinol. 1989 Jul;3(7):1108-14
J:88555 Paliwal S, et al., P311 binds to the latency associated protein and downregulates the expression of TGF-beta1 and TGF-beta2. Biochem Biophys Res Commun. 2004 Mar 19;315(4):1104-9
J:88556 Oka C, et al., HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins. Development. 2004 Mar;131(5):1041-53
J:91306 Tocharus J, et al., Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling. Dev Growth Differ. 2004 Jun;46(3):257-74
J:203960 Combs MD, et al., Microfibril-associated glycoprotein 2 (MAGP2) loss of function has pleiotropic effects in vivo. J Biol Chem. 2013 Oct 4;288(40):28869-80