Sequence Detail

ID/Version

P26687 (UniProt | EBI)

Last sequence update: 1992-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Twist-related protein 1;AltName: Full=M-twist;

Provider

SWISS-PROT

Sequence

Polypeptide 206 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Twist1	twist basic helix-loop-helix transcription factor 1	139	203	4	19

Sequence references in MGI

J:10970 Wolf C, et al., The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes. Dev Biol. 1991 Feb;143(2):363-73
J:81485 Sosic D, et al., Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell. 2003 Jan 24;112(2):169-80
J:87212 Hamamori Y, et al., The basic domain of myogenic basic helix-loop-helix (bHLH) proteins is the novel target for direct inhibition by another bHLH protein, Twist. Mol Cell Biol. 1997 Nov;17(11):6563-73
J:108218 Connerney J, et al., Twist1 dimer selection regulates cranial suture patterning and fusion. Dev Dyn. 2006 May;235(5):1334-46
J:161110 Laursen KB, et al., Mechanism of transcriptional activation by the proto-oncogene Twist1. J Biol Chem. 2007 Nov 30;282(48):34623-33
J:207820 Curtis AM, et al., Histone acetyltransferase-dependent chromatin remodeling and the vascular clock. J Biol Chem. 2004 Feb 20;279(8):7091-7
J:302456 Davies OR, et al., Tcf15 primes pluripotent cells for differentiation. Cell Rep. 2013 Feb 21;3(2):472-84