Sequence Detail

ID/Version

P25799 Q3V2V6 B2RRQ6 Q3TZE8 Q80Y21 Q6TDG8 Q8C712 Q75ZL1 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Nuclear factor NF-kappa-B p105 subunit;AltName: Full=DNA-binding factor KBF1;AltName: Full=EBP-1;AltName: Full=NF-kappa-B1 p84/NF-kappa-B1 p98;AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1;Contains: RecN

Provider

SWISS-PROT

Sequence

Polypeptide 971 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	123	113	3	75

Sequence references in MGI

J:2282 Inoue J, et al., I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family. Cell. 1992 Mar 20;68(6):1109-20
J:18136 Grumont RJ, et al., Alternative splicing of RNA transcripts encoded by the murine p105 NF-kappa B gene generates I kappa B gamma isoforms with different inhibitory activities. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4367-71
J:21614 Grumont RJ, et al., Alternate RNA splicing of murine nfkb1 generates a nuclear isoform of the p50 precursor NF-kappa B1 that can function as a transactivator of NF-kappa B-regulated transcription. Mol Cell Biol. 1994 Dec;14(12):8460-70
J:25020 Ghosh S, et al., Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal. Cell. 1990 Sep 7;62(5):1019-29
J:75807 Fiorini E, et al., Peptide-induced negative selection of thymocytes activates transcription of an NF-kappaB inhibitor. Mol Cell. 2002 Mar;9(3):637-48
J:91297 Yamamoto M, et al., Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta. Nature. 2004 Jul 8;430(6996):218-22
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:135247 Minami M, et al., Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation. J Biol Chem. 2008 Apr 11;283(15):9692-703
J:230368 Chen-Park FE, et al., The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription. J Biol Chem. 2002 Jul 5;277(27):24701-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89