About   Help   FAQ
Sequence Detail
P25446 Q6GT31 Q9DCQ1 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2018-09-12
from provider
RecName: Full=Tumor necrosis factor receptor superfamily member 6;AltName: Full=Apo-1 antigen;AltName: Full=Apoptosis-mediating surface antigen FAS;AltName: Full=FASLG receptor;AltName: CD_antigen=CD95;Flags: Precursor;
Polypeptide 327 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Fas Fas (TNF receptor superfamily member 6) 105 4 9 15
Sequence references in MGI J:1181 Watanabe-Fukunaga R, et al., Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature. 1992 Mar 26;356(6367):314-7
J:2292 Watanabe-Fukunaga R, et al., The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J Immunol. 1992 Feb 15;148(4):1274-9
J:4342 Adachi M, et al., Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1756-60
J:41242 Yang X, et al., Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell. 1997 Jun 27;89(7):1067-76
J:65176 Rochat-Steiner V, et al., FIST/HIPK3. A Fas/fadd-interacting serine/threonine kinase that induces fadd phosphorylation and inhibits fas-mediated jun nh(2)-terminal kinase activation. J Exp Med. 2000 Oct 16;192(8):1165-74
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:122193 Villa-Morales M, et al., A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas. Cancer Res. 2007 Jun 1;67(11):5107-16
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:199564 Baeza-Raja B, et al., p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks. J Neurosci. 2013 Jun 19;33(25):10221-34
J:217283 Nam YJ, et al., Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions. Mol Cell. 2004 Sep 24;15(6):901-12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.12
The Jackson Laboratory