Sequence Detail

ID/Version

P25206 Q61492 (UniProt | EBI)

Last sequence update: 1997-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=DNA replication licensing factor MCM3; EC=3.6.4.12;AltName: Full=DNA polymerase alpha holoenzyme-associated protein P1 {ECO:0000303|PubMed:7925275};AltName: Full=P1-MCM3 {ECO:0000303|PubMed:7925275};

Provider

SWISS-PROT

Sequence

Polypeptide 812 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mcm3	minichromosome maintenance complex component 3	43	106	3	12

Sequence references in MGI

J:20543 Kimura H, et al., DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. EMBO J. 1994 Sep 15;13(18):4311-20
J:20884 Thommes P, et al., Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein. Nucleic Acids Res. 1992 Mar 11;20(5):1069-74
J:62649 Kuwahara K, et al., A novel nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication. Blood. 2000 Apr 1;95(7):2321-8
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89