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Sequence Detail
P25118 (UniProt | EBI) Last sequence update: 1992-05-01
Last annotation update: 2021-02-10
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RecName: Full=Tumor necrosis factor receptor superfamily member 1A;AltName: Full=Tumor necrosis factor receptor 1; Short=TNF-R1;AltName: Full=Tumor necrosis factor receptor type I; Short=TNF-RI; Short=TNFR-I;AltName: Full=p55;AltNa
Polypeptide 454 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 77 79 9 22
Sequence references in MGI J:3640 Rothe J, et al., Genomic organization and promoter function of the murine tumor necrosis factor receptor beta gene. Mol Immunol. 1993 Feb;30(2):165-75
J:11097 Lewis M, et al., Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc Natl Acad Sci U S A. 1991 Apr 1;88(7):2830-4
J:11207 Goodwin RG, et al., Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor. Mol Cell Biol. 1991 Jun;11(6):3020-6
J:11534 Rothe JG, et al., Molecular cloning and expression of the mouse Tnf receptor type b. Immunogenetics. 1991;34(5):338-40
J:17931 Barrett K, et al., Cloning, expression and cross-linking analysis of the murine p55 tumor necrosis factor receptor. Eur J Immunol. 1991 Jul;21(7):1649-56
J:18317 Bebo BF Jr, et al., Nucleotide sequence of the TNF type I receptor from a mouse endothelioma cell line. Immunogenetics. 1994;39(6):450-1
J:218360 Kung G, et al., A novel role for the apoptosis inhibitor ARC in suppressing TNFalpha-induced regulated necrosis. Cell Death Differ. 2014 Apr;21(4):634-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory