Sequence Detail

ID/Version

P24549 Q7TQJ0 Q811J0 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Aldehyde dehydrogenase 1A1 {ECO:0000305|PubMed:12851412}; EC=1.2.1.19 {ECO:0000305|PubMed:26430123}; EC=1.2.1.28 {ECO:0000250|UniProtKB:P00352}; EC=1.2.1.3 {ECO:0000269|PubMed:12851412}; EC=1.2.1.36 {ECO:00002

Provider

SWISS-PROT

Sequence

Polypeptide 501 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	61	172	2	10

Sequence references in MGI

J:20371 Bond SL, et al., DNA sequence analysis of the cytosolic acetaldehyde dehydrogenase gene (Ahd-2) in mouse strains with variable ethanol preferences. Biochem Med Metab Biol. 1994 Aug;52(2):155-9
J:32119 McCaffery P, et al., Aldehyde dehydrogenase is a positional marker in the retina. Development. 1991 Jul;112(3):693-702
J:36510 Rongnoparut P, et al., Isolation and characterization of a cytosolic aldehyde dehydrogenase-encoding cDNA from mouse liver. Gene. 1991 May 30;101(2):261-5
J:85538 Molotkov A, et al., Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid. J Biol Chem. 2003 Sep 19;278(38):36085-90
J:124711 Lassen N, et al., Multiple and Additive Functions of ALDH3A1 and ALDH1A1: CATARACT PHENOTYPE AND OCULAR OXIDATIVE DAMAGE IN Aldh3a1(-/-)/Aldh1a1(-/-) KNOCK-OUT MICE. J Biol Chem. 2007 Aug 31;282(35):25668-76
J:226538 Kim JI, et al., Aldehyde dehydrogenase 1a1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons. Science. 2015 Oct 2;350(6256):102-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89