Sequence Detail

ID/Version

P24527 Q3UY71 Q8VDR8 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Leukotriene A-4 hydrolase; Short=LTA-4 hydrolase; EC=3.3.2.6 {ECO:0000269|PubMed:1881903, ECO:0000269|PubMed:9287304};AltName: Full=Leukotriene A(4) hydrolase;AltName: Full=Tripeptide aminopeptidase LTA4H; EC=3.4.11.4

Provider

SWISS-PROT

Sequence

Polypeptide 611 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lta4h	leukotriene A4 hydrolase	56	99	3	17

Sequence references in MGI

J:11211 Medina JF, et al., Molecular cloning and expression of mouse leukotriene A4 hydrolase cDNA. Biochem Biophys Res Commun. 1991 May 15;176(3):1516-24
J:58985 Byrum RS, et al., Determination of the contribution of cysteinyl leukotrienes and leukotriene B4 in acute inflammatory responses using 5-lipoxygenase- and leukotriene A4 hydrolase-deficient mice. J Immunol. 1999 Dec 15;163(12):6810-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:164434 Snelgrove RJ, et al., A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation. Science. 2010 Oct 1;330(6000):90-4
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89