Sequence Detail

ID/Version

P24383 Q80VH3 Q9DBY3 (UniProt | EBI)

Last sequence update: 2011-06-28
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Protein Wnt-7a;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 349 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wnt7a	wingless-type MMTV integration site family, member 7A	124	167	3	17

Sequence references in MGI

J:10971 Gavin BJ, et al., Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec;4(12B):2319-32
J:23922 Parr BA, et al., Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature. 1995 Mar 23;374(6520):350-3
J:50342 Parr BA, et al., Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a. Nature. 1998 Oct 15;395(6703):707-10
J:50461 Parr BA, et al., The classical mouse mutant postaxial hemimelia results from a mutation in the Wnt 7a gene. Dev Biol. 1998 Oct 15;202(2):228-34
J:63226 Tanaka K, et al., The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem. 2000 Jul;267(13):4300-11
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:204487 Qu Q, et al., Wnt7a regulates multiple steps of neurogenesis. Mol Cell Biol. 2013 Jul;33(13):2551-9
J:256044 Cho C, et al., Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation. Neuron. 2017 Aug 30;95(5):1056-1073.e5