Sequence Detail

ID/Version

P24063 E9Q5M7 Q3U159 E9QNL8 (UniProt | EBI)

Last sequence update: 2022-02-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Integrin alpha-L {ECO:0000305};AltName: Full=CD11 antigen-like family member A;AltName: Full=Leukocyte adhesion glycoprotein LFA-1 alpha chain; Short=LFA-1A;AltName: Full=Leukocyte function-associated molecule 1 alpha chain;AltName:

Provider

SWISS-PROT

Sequence

Polypeptide 1162 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Itgal	integrin alpha L	41	100	3	16

Sequence references in MGI

J:11253 Kaufmann Y, et al., Cloning of the murine lymphocyte function-associated molecule-1 alpha-subunit and its expression in COS cells. J Immunol. 1991 Jul 1;147(1):369-74
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:127587 Liu Z, et al., Differential roles for beta2 integrins in experimental autoimmune bullous pemphigoid. Blood. 2006 Feb 1;107(3):1063-9
J:244645 Bose TO, et al., CD11a is essential for normal development of hematopoietic intermediates. J Immunol. 2014 Sep 15;193(6):2863-72
J:246691 Jiang E, et al., Essential role of CD11a in CD8+ T-cell accumulation and activation in adipose tissue. Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):34-43
J:251888 Swaim CD, et al., Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor. Mol Cell. 2017 Nov 2;68(3):581-590.e5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89