Sequence Detail

ID/Version

P23906 (UniProt | EBI)

Last sequence update: 1991-11-01
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Interferon regulatory factor 2; Short=IRF-2;

Provider

SWISS-PROT

Sequence

Polypeptide 349 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Irf2	interferon regulatory factor 2	51	102	4	11

Sequence references in MGI

J:15789 Uegaki K, et al., Characterization of the DNA binding domain of the mouse IRF-2 protein. Protein Eng. 1993 Feb;6(2):195-200
J:17557 Harada H, et al., Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell. 1989 Aug 25;58(4):729-39
J:64286 Matsuyama T, et al., Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell. 1993 Oct 8;75(1):83-97
J:371697 Harada H, et al., Absence of the type I IFN system in EC cells: transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated. Cell. 1990 Oct 19;63(2):303-12