Sequence Detail

ID/Version

P23242 Q544I7 P23242 (UniProt | EBI)

Last sequence update: 2007-01-23 Last annotation update: 2013-05-29

Sequence description from provider

RecName: Full=Gap junction alpha-1 protein;AltName: Full=Connexin-43; Short=Cx43;AltName: Full=Gap junction 43 kDa heart protein;

Provider

SWISS-PROT

Sequence

Polypeptide 382 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gja1	gap junction protein, alpha 1	106	48	5	59

Sequence references in MGI

J:1099 Hennemann H, et al., Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung. J Cell Biol. 1992 Jun;117(6):1299-310
J:11145 Beyer EC, et al., Evidence that the gap junction protein connexin-43 is the ATP-induced pore of mouse macrophages. J Biol Chem. 1991 May 5;266(13):7971-4
J:14428 Sullivan R, et al., Structure, sequence and expression of the mouse Cx43 gene encoding connexin 43. Gene. 1993 Aug 25;130(2):191-9
J:33509 Nishi M, et al., Developmental regulation of gap junction gene expression during mouse embryonic development. Dev Biol. 1991 Jul;146(1):117-30
J:73509 Liu XZ, et al., Mutations in GJA1 (connexin 43) are associated with non-syndromic autosomal recessive deafness. Hum Mol Genet. 2001 Dec 1;10(25):2945-51
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114712 Lan Z, et al., Novel rab GAP-like protein, CIP85, interacts with connexin43 and induces its degradation. Biochemistry. 2005 Feb 22;44(7):2385-96
J:155343 del Castillo FJ, et al., Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins. Hum Mol Genet. 2010 Jan 15;19(2):262-75
J:184186 Straub AC, et al., Compartmentalized connexin 43 s-nitrosylation/denitrosylation regulates heterocellular communication in the vessel wall. Arterioscler Thromb Vasc Biol. 2011 Feb;31(2):399-407
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93