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Sequence Detail
ID/Version
P23204 (UniProt | EBI) Last sequence update: 1996-10-01
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Peroxisome proliferator-activated receptor alpha; Short=PPAR-alpha;AltName: Full=Nuclear receptor subfamily 1 group C member 1;
Provider SWISS-PROT
Sequence
Polypeptide 468 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ppara peroxisome proliferator activated receptor alpha 131 141 4 20
Sequence references in MGI J:10775 Issemann I, et al., Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators [see comments]. Nature. 1990 Oct 18;347(6294):645-50
J:17040 Gearing KL, et al., Structure of the mouse peroxisome proliferator activated receptor alpha gene. Biochem Biophys Res Commun. 1994 Feb 28;199(1):255-63
J:29812 Jones PS, et al., Chromosomal localisation, inducibility, tissue-specific expression and strain differences in three murine peroxisome-proliferator-activated-receptor genes. Eur J Biochem. 1995 Oct 1;233(1):219-26
J:43438 Zhu Y, et al., Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor. J Biol Chem. 1997 Oct 10;272(41):25500-6
J:62059 Zhu Y, et al., Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR. J Biol Chem. 2000 May 5;275(18):13510-6
J:85352 Fu J, et al., Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha. Nature. 2003 Sep 4;425(6953):90-3
J:129744 Finck BN, et al., Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway. Cell Metab. 2006 Sep;4(3):199-210
J:138823 Seale P, et al., PRDM16 controls a brown fat/skeletal muscle switch. Nature. 2008 Aug 21;454(7207):961-7
J:156994 Schmutz I, et al., The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors. Genes Dev. 2010 Feb 15;24(4):345-57
J:157324 Chakravarthy MV, et al., Identification of a physiologically relevant endogenous ligand for PPARalpha in liver. Cell. 2009 Aug 7;138(3):476-88
J:255965 Jordan SD, et al., CRY1/2 Selectively Repress PPARdelta and Limit Exercise Capacity. Cell Metab. 2017 Jul 5;26(1):243-255.e6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory