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Sequence Detail
ID/Version
P23188 Q6GTN6 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2019-06-05
Sequence
description
from provider
RecName: Full=Furin; EC=3.4.21.75 {ECO:0000250|UniProtKB:P09958};AltName: Full=Dibasic-processing enzyme;AltName: Full=Paired basic amino acid residue-cleaving enzyme; Short=PACE;AltName: Full=Prohormone convertase 3;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 793 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Furin furin (paired basic amino acid cleaving enzyme) 55 6 10 11
Sequence references in MGI J:23406 Hatsuzawa K, et al., Structure and expression of mouse furin, a yeast Kex2-related protease. Lack of processing of coexpressed prorenin in GH4C1 cells. J Biol Chem. 1990 Dec 25;265(36):22075-8
J:51716 Liu G, et al., Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway. J Cell Biol. 1997 Dec 29;139(7):1719-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory