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Sequence Detail
P22777 (UniProt | EBI) Last sequence update: 1991-08-01
Last annotation update: 2018-02-28
from provider
RecName: Full=Plasminogen activator inhibitor 1; Short=PAI; Short=PAI-1;AltName: Full=Endothelial plasminogen activator inhibitor;AltName: Full=Serpin E1;Flags: Precursor;
Polypeptide 402 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 65 9 8 8
Sequence references in MGI J:32471 Prendergast GC, et al., The c-myc-regulated gene mrl encodes plasminogen activator inhibitor 1. Mol Cell Biol. 1990 Mar;10(3):1265-9
J:198078 Oishi K, et al., The molecular clock regulates circadian transcription of tissue factor gene. Biochem Biophys Res Commun. 2013 Feb 8;431(2):332-5
J:248177 Jiang C, et al., Serpine 1 induces alveolar type II cell senescence through activating p53-p21-Rb pathway in fibrotic lung disease. Aging Cell. 2017 Oct;16(5):1114-1124

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory