Sequence Detail

ID/Version

P22777 (UniProt | EBI)

Last sequence update: 1991-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Plasminogen activator inhibitor 1; Short=PAI; Short=PAI-1;AltName: Full=Endothelial plasminogen activator inhibitor;AltName: Full=Serpin E1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 402 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	79	109	3	15

Sequence references in MGI

J:32471 Prendergast GC, et al., The c-myc-regulated gene mrl encodes plasminogen activator inhibitor 1. Mol Cell Biol. 1990 Mar;10(3):1265-9
J:198078 Oishi K, et al., The molecular clock regulates circadian transcription of tissue factor gene. Biochem Biophys Res Commun. 2013 Feb 8;431(2):332-5
J:248177 Jiang C, et al., Serpine 1 induces alveolar type II cell senescence through activating p53-p21-Rb pathway in fibrotic lung disease. Aging Cell. 2017 Oct;16(5):1114-1124