Sequence Detail

ID/Version

P22723 Q91VA8 Q91V50 (UniProt | EBI)

Last sequence update: 2002-03-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Gamma-aminobutyric acid receptor subunit gamma-2;AltName: Full=GABA(A) receptor subunit gamma-2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 474 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gabrg2	gamma-aminobutyric acid type A receptor, subunit gamma 2	62	112	3	25

Sequence references in MGI

J:10953 Kofuji P, et al., Generation of two forms of the gamma-aminobutyric acidA receptor gamma 2-subunit in mice by alternative splicing. J Neurochem. 1991 Feb;56(2):713-5
J:66632 Hood HM, et al., Allelic variation in the GABA A receptor gamma2 subunit is associated with genetic susceptibility to ethanol-induced motor incoordination and hypothermia, conditioned taste aversion, and withdrawal in BXD/Ty recombinant inbred mice. Alcohol Clin Exp Res. 2000 Sep;24(9):1327-34
J:211247 Saras A, et al., Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses. J Biol Chem. 2008 Apr 18;283(16):10470-5
J:254795 Davenport EC, et al., An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors. Cell Rep. 2017 Oct 3;21(1):70-83
J:256156 Yamasaki T, et al., GARLH Family Proteins Stabilize GABAA Receptors at Synapses. Neuron. 2017 Mar 8;93(5):1138-1152.e6
J:265620 Wu M, et al., Impairment of Inhibitory Synapse Formation and Motor Behavior in Mice Lacking the NL2 Binding Partner LHFPL4/GARLH4. Cell Rep. 2018 May 8;23(6):1691-1705
J:281261 Brown LE, et al., gamma-Aminobutyric Acid Type A (GABAA) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains. J Biol Chem. 2016 Jul 1;291(27):13926-42
J:281687 Han W, et al., Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions. Science. 2019 Oct 11;366(6462):246-250
J:285011 Fang C, et al., GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses. J Neurosci. 2006 Dec 6;26(49):12758-68