Sequence Detail

ID/Version

P21812 Q9EPQ9 Q9EQT2 (UniProt | EBI)

Last sequence update: 1991-05-01
Last annotation update: 2023-11-08

Sequence description from provider

RecName: Full=Mast cell protease 4; Short=mMCP-4; EC=3.4.21.-;AltName: Full=MSMCP;AltName: Full=Myonase;AltName: Full=Serosal mast cell protease;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 246 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mcpt4	mast cell protease 4	8	97	19	6

Sequence references in MGI

J:10948 Serafin WE, et al., Cloning of the cDNA and gene for mouse mast cell protease 4. Demonstration of its late transcription in mast cell subclasses and analysis of its homology to subclass-specific neutral proteases of the mouse and rat. J Biol Chem. 1991 Jan 25;266(3):1934-41
J:11290 Huang RY, et al., Cloning and structural analysis of MMCP-1, MMCP-4 and MMCP-5, three mouse mast cell-specific serine proteases. Eur J Immunol. 1991 Jul;21(7):1611-21
J:17707 Reynolds DS, et al., Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases. Proc Natl Acad Sci U S A. 1990 Apr;87(8):3230-4
J:34030 Newlands GF, et al., Biochemical and immunological characterization of multiple glycoforms of mouse mast cell protease 1: comparison with an isolated murine serosal mast cell protease (MMCP-4). Biochem J. 1993 Aug 15;294(Pt 1):127-35
J:47241 Hori S, et al., Purification and characterization of myonase from X-chromosome linked muscular dystrophic mouse skeletal muscle. J Biochem. 1998 Apr;123(4):650-8
J:67337 Ge Y, et al., Independent influence of strain difference and mi transcription factor on the expression of mouse mast cell chymases. Am J Pathol. 2001 Jan;158(1):281-92
J:84839 Tchougounova E, et al., The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover. J Exp Med. 2003 Aug 4;198(3):423-31