Sequence Detail

ID/Version

P21803 Q00389 Q61342 O55141 (UniProt | EBI)

Last sequence update: 1997-11-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Fibroblast growth factor receptor 2; Short=FGFR-2; EC=2.7.10.1;AltName: Full=Keratinocyte growth factor receptor; Short=KGFR;AltName: CD_antigen=CD332;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 821 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fgfr2	fibroblast growth factor receptor 2	186	265	3	70

Sequence references in MGI

J:502 Mansukhani A, et al., Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3305-9
J:9737 Kornbluth S, et al., Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries. Mol Cell Biol. 1988 Dec;8(12):5541-4
J:10921 Miki T, et al., Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop. Science. 1991 Jan 4;251(4989):72-5
J:13170 Orr-Urtreger A, et al., Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2). Dev Biol. 1993 Aug;158(2):475-86
J:36463 Raz V, et al., PCR-based identification of new receptors: molecular cloning of a receptor for fibroblast growth factors. Oncogene. 1991 May;6(5):753-60
J:46380 Xu X, et al., Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development. 1998 Feb;125(4):753-65
J:47643 Arman E, et al., Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5082-7
J:58117 Arman E, et al., Fgfr2 is required for limb outgrowth and lung-branching morphogenesis. Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11895-9
J:77698 Eswarakumar VP, et al., The IIIc alternative of Fgfr2 is a positive regulator of bone formation. Development. 2002 Aug 15;129(16):3783-93