Sequence Detail

ID/Version

P20109 (UniProt | EBI)

Last sequence update: 1991-02-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Interleukin-13; Short=IL-13;AltName: Full=T-cell activation protein P600;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 131 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Il13	interleukin 13	57	102	3	28

Sequence references in MGI

J:20635 Brown KD, et al., A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes. J Immunol. 1989 Jan 15;142(2):679-87
J:38364 Takeda K, et al., Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice. J Immunol. 1996 Oct 15;157(8):3220-2
J:244446 Edukulla R, et al., Th2 Cytokines Augment IL-31/IL-31RA Interactions via STAT6-dependent IL-31RA Expression. J Biol Chem. 2015 May 22;290(21):13510-20
J:257624 Duffen J, et al., Modulation of the IL-33/IL-13 Axis in Obesity by IL-13Ralpha2. J Immunol. 2018 Feb 15;200(4):1347-1359
J:317180 Zhang M, et al., IL-13 Controls IL-33 Activity through Modulation of ST2. J Immunol. 2021 Nov 17;207(12):3070-3080
J:321392 Mayer JU, et al., Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization. Nat Immunol. 2021 Dec;22(12):1538-1550