Sequence Detail

ID/Version

P19096 Q6PB72 B1ATU8 Q8C4Z0 Q9EQR0 (UniProt | EBI)

Last sequence update: 2004-10-11
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Fatty acid synthase; EC=2.3.1.85 {ECO:0000269|PubMed:29328619};AltName: Full=Type I Fatty Acid Synthase {ECO:0000303|PubMed:31811668};Includes: RecName: Full=[Acyl-carrier-protein] S-acetyltransferase; EC=2.3.1.38 {ECO:000

Provider

SWISS-PROT

Sequence

Polypeptide 2504 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fasn	fatty acid synthase	84	114	3	25

Sequence references in MGI

J:24535 Paulauskis JD, et al., Structure of mouse fatty acid synthase mRNA. Identification of the two NADPH binding sites. Biochem Biophys Res Commun. 1989 Feb 15;158(3):690-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:376108 Rittner A, et al., Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering. ACS Chem Biol. 2018 Mar 16;13(3):723-732