Sequence Detail

ID/Version

P18165 Q8R0I9 (UniProt | EBI)

Last sequence update: 2004-03-15
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Loricrin {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 486 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Loricrin	loricrin cornified envelope precursor protein	11	152	1	6

Sequence references in MGI

J:17951 Mehrel T, et al., Identification of a major keratinocyte cell envelope protein, loricrin. Cell. 1990 Jun 15;61(6):1103-12
J:25080 DiSepio D, et al., The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression. J Biol Chem. 1995 May 5;270(18):10792-9
J:65188 Suga Y, et al., Transgenic mice expressing a mutant form of loricrin reveal the molecular basis of the skin diseases, vohwinkel syndrome and progressive symmetric erythrokeratoderma. J Cell Biol. 2000 Oct 16;151(2):401-12
J:214772 Fischer H, et al., Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation. J Invest Dermatol. 2014 Oct;134(10):2579-88
J:297664 Simonson L, et al., Keratin 13 deficiency causes white sponge nevus in mice. Dev Biol. 2020 Dec 1;468(1-2):146-153