Sequence Detail

ID/Version

P16056 Q62125 (UniProt | EBI)

Last sequence update: 1990-04-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Hepatocyte growth factor receptor; Short=HGF receptor; EC=2.7.10.1;AltName: Full=HGF/SF receptor;AltName: Full=Proto-oncogene c-Met;AltName: Full=Scatter factor receptor; Short=SF receptor;AltName: Full=Tyrosine-prote

Provider

SWISS-PROT

Sequence

Polypeptide 1379 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Met	met proto-oncogene	109	159	3	32

Sequence references in MGI

J:4635 Weidner KM, et al., The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells. J Cell Biol. 1993 Apr;121(1):145-54
J:13364 Chan AM, et al., Characterization of the mouse met proto-oncogene. Oncogene. 1988 Jun;2(6):593-9
J:22689 Wilks AF, et al., The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family. Gene. 1989 Dec 21;85(1):67-74
J:28570 Bladt F, et al., Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud [see comments]. Nature. 1995 Aug 31;376(6543):768-71
J:92782 Higuchi T, et al., MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met. Mol Cell Biol. 2004 Sep;24(17):7456-68
J:230730 Gray MJ, et al., Mutations Preventing Regulated Exon Skipping in MET Cause Osteofibrous Dysplasia. Am J Hum Genet. 2015 Dec 3;97(6):837-47
J:245316 Masters SL, et al., The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues. Nat Struct Mol Biol. 2006 Jan;13(1):77-84
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89