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Sequence Detail
ID/Version
P15864 (UniProt | EBI) Last sequence update: 2007-01-23
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Histone H1.2;AltName: Full=H1 VAR.1;AltName: Full=H1c;
Provider SWISS-PROT
Sequence
Polypeptide 212 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene H1f2 H1.2 linker histone, cluster member 22 100 17 4
Sequence references in MGI J:19075 Yang YS, et al., Isolation and characterization of a mouse fully replication-dependent H1 gene within a genomic cluster of core histone genes. J Biol Chem. 1987 Dec 15;262(35):17118-25
J:19284 Cheng GH, et al., Different 3'-end processing produces two independently regulated mRNAs from a single H1 histone gene. Proc Natl Acad Sci U S A. 1989 Sep;86(18):7002-6
J:49367 Franke K, et al., Expression of murine H1 histone genes during postnatal development. Biochim Biophys Acta. 1998 Jul 9;1398(3):232-42
J:80094 Marzluff WF, et al., The human and mouse replication-dependent histone genes. Genomics. 2002 Nov;80(5):487-98
J:83954 Fan Y, et al., H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo. Mol Cell Biol. 2003 Jul;23(13):4559-72
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:205556 Christophorou MA, et al., Citrullination regulates pluripotency and histone H1 binding to chromatin. Nature. 2014 Mar 6;507(7490):104-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory