Sequence Detail

ID/Version

P15806 Q8VCY4 Q922S2 Q3U153 Q99MB8 Q9CYJ4 Q8CAH9 (UniProt | EBI)

Last sequence update: 2004-08-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transcription factor E2-alpha;AltName: Full=Immunoglobulin enhancer-binding factor E12/E47;AltName: Full=Transcription factor 3; Short=TCF-3;AltName: Full=Transcription factor A1;

Provider

SWISS-PROT

Sequence

Polypeptide 651 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tcf3	transcription factor 3	150	121	4	65

Sequence references in MGI

J:17006 Kajimoto Y, et al., Identification of amino-acid polymorphism within the leucine zipper motif of mouse transcription factor A1. Gene. 1994 Feb 25;139(2):247-9
J:17285 Walker MD, et al., A cDNA from a mouse pancreatic beta cell encoding a putative transcription factor of the insulin gene. Nucleic Acids Res. 1990 Mar 11;18(5):1159-66
J:23303 Watada H, et al., Ubiquitous, but variable, expression of two alternatively spliced mRNAs encoding mouse homologues of transcription factors E47 and E12. Gene. 1995 Feb 14;153(2):255-9
J:29655 Li L, et al., Dermo-1: a novel twist-related bHLH protein expressed in the developing dermis. Dev Biol. 1995 Nov;172(1):280-92
J:44342 Loveys DA, et al., The mUBC9 murine ubiquitin conjugating enzyme interacts with the E2A transcription factors. Gene. 1997 Nov 12;201(1-2):169-77
J:62777 Obata J, et al., p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos. Genes Cells. 2001 Apr;6(4):345-60
J:80041 Heng JI, et al., Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain. J Biol Chem. 2002 Nov 8;277(45):43152-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134786 Ravanpay AC, et al., E protein dosage influences brain development more than family member identity. J Neurosci Res. 2008 May 15;86(7):1472-81
J:200299 Goardon N, et al., ETO2 coordinates cellular proliferation and differentiation during erythropoiesis. EMBO J. 2006 Jan 25;25(2):357-66
J:210057 Ejarque M, et al., Characterization of the transcriptional activity of the basic helix-loop-helix (bHLH) transcription factor Atoh8. Biochim Biophys Acta. 2013 Nov;1829(11):1175-83
J:279055 He B, et al., Identification of the Novel Tooth-Specific Transcription Factor AmeloD. J Dent Res. 2019 Feb;98(2):234-241
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:302448 Wilson-Rawls J, et al., Paraxis is a basic helix-loop-helix protein that positively regulates transcription through binding to specific E-box elements. J Biol Chem. 2004 Sep 3;279(36):37685-92
J:302456 Davies OR, et al., Tcf15 primes pluripotent cells for differentiation. Cell Rep. 2013 Feb 21;3(2):472-84
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87